Insulin resistance protects against…insulin! T2D 26

posted in: Diabetes, Health and Nutrition | 66

Virtually all doctors agree that elevated insulin resistance is very bad for human health, being the root cause of type 2 diabetes and metabolic syndrome. So, if it is so bad, why do we all develop it in the first place? How can such a mal-adaptive process be so ubiquitous?

As of 2015, over 50% of the American population has diabetes or pre-diabetes. This stunning statistic means that there are more people in the United States with pre-diabetes or diabetes than without it. It’s the new normal. Why does it develop it so frequently? There must be some protective purpose to it since our bodies are not designed to fail. Humans have lived for millennia before the modern diabesity epidemic. How can insulin resistance be protective?

Insulin resistance

You can discover many things by taking a different perspective. The golden rule states “Do unto others as you would have them do unto you.” A well-known quote says, “Before you judge me, walk a mile in my shoes”. In both cases, the key to success is change perspective. Invert (turn upside down) your perspective, and see how your horizons are immensely broadened. So let’s look at the development of insulin resistance from the opposite angle. Let’s not consider why insulin resistance is bad, but rather, why it is good.

It is a well-established fact that high blood glucose levels are harmful. But here’s a question seldom asked. If the high glucose level is toxic in the blood, why wouldn’t it also be toxic inside the cells? As glucose enters the cells faster than it can be used for energy, it accumulates inside the cell.

Insulin’s moves glucose from the blood into the cells, but doesn’t actually eliminate it from the body. It merely shoves the excess glucose out of the blood and forces it into the body. Somewhere. Anywhere. Eyes. Kidneys. Nerves. Heart.

Let’s consider an analogy. We all need food, but if there’s too much lying around, it simply rots. As the amount of rotten garbage piles up, we need to throw it out. Moving it under the sink, where it is out of sight, is not ultimately useful. We might not be able to see it and pretend that our kitchen is still nice and clean, but eventually the entire house is starting to stink.

The same logic applies to the excessive glucose. Using medications like insulin to hide the blood glucose into the tissues of the body is ultimately destructive since it cannot be disposed of properly.

A trip to DiabetesVille

Imagine that you live in a town called DiabetesVille. Like cells in our body, there are many houses on Liver Street, Kidney Road, and Pancreatic Avenue among others. Everybody is friendly and normally leaves their door open and unlocked. Three times a day, a glucose truck comes down the street and Mr. Insulin delivers a small cup of glucose to each house. Life is going well, and everybody is happy.

But gradually, over time, Mr. Insulin comes around more and more often. Instead of three times, he comes six times a day. Instead of dropping off a little cupful of glucose, he drops whole heaping barrels of the stuff. He needs to empty his truck every night, or else he’ll lose his job. For a while, you take the excess glucose into your house and life goes on.

Finally, your house is completely filled with glucose, which is starting to rot and stinking up the house. Like everything else in life, the dose makes the poison. A little glucose is OK, but too much is toxic.

You try to reason with Mr. Insulin, but to no avail. Every house on every street is experiencing the same situation. When that glucose truck comes down the street, Mr. Insulin really needs to get rid of this toxic waste. Every time a door is open, he shovels in another barrelful of glucose.

‘Toxic Waste Disposal, satisfaction guaranteed or double your waste back.’

Now, what would you do? You’d bar your door, is what you’d do! You’d shout, “I don’t want this toxic glucose! I’ve got too much already, and I don’t want anymore.” You lock the front door so that it is difficult for Mr. Insulin to shove more toxic stuff into your house. It’s not a bad thing; it’s a good thing. You are simply protecting your house from Mr. Insulin’s toxic glucose load. That’s insulin resistance!

An outside observer would only see that Mr. Insulin is trying to do its job of moving glucose into the house, but is unable to do so. He may erroneously conclude that this house is ‘resistant’ to insulin because the door is broken (lock and key paradigm). But in reality, the problem was that there was already too much glucose inside.

Mr. Insulin is now finding it harder and harder to get rid of his glucose load and is worried he’s going to get fired. So, he asks his brothers to help him. The Insulin brothers team up to break down the door so they can shovel in barrels of glucose into your unwilling home. This works, but only for a while, as you race to reinforce your front door with steel bars to increase resistance.

Suppose we eat a diet very high in sugar over many years. Glucose and fructose are entering our body in excess of our energy needs, stimulating insulin. Glucose is flooding the liver, which stores some as glycogen. When glycogen stores are full, the liver turns on de novo lipogenesis and creates new fat. But the rate of production exceeds the liver’s capacity to export it, so fat is accumulating in the liver, where it should not be.

Insulin tries to move the toxic glucose into the liver, but it doesn’t want it either. The liver cells try to protect themselves against this excessive glucose load by increasing insulin resistance. This is a protective mechanism.

What, exactly is insulin resistance protecting us from? Its very name gives the answer away. Insulin Resistance. It’s a reaction against excessive insulin. It’s protecting us from the excessive insulin. Insulin causes insulin resistance.

This sets off a vicious reactionary cycle, where insulin resistance leads to further hyperinsulinemia, leading only to further resistance. But the root cause is the hyperinsulinemia, not the insulin resistance. The cells of they body tissues (heart, nerves, kidney, eyes) are all busy increasing their resistance to protect themselves from insulin. The resistance is only a response to the hyperinsulinemia.

Dr. Endo steps in

Back in DiabetesVille, Mr. Insulin and his gang are not able to unload their huge glucose burden. All the doors have been triple barred and guarded by dogs. Glucose is spilling over into the streets. Unsure what else to do, the specialist Dr. Endocrine steps in. Dr. Endo decides that the glucose is indeed toxic, and the streets must be cleared immediately.

Despite the fact that there are hoards of Insulin clansmen prowling the streets, Dr. Endo decides that the best solution is to use even more insulin! Since Mr. Insulin has no more family, Dr. Endo hires more henchmen to do the job. They shove more toxic glucose into the reluctant houses, clearing off the streets.

At least Dr. Endo cannot see the problem anymore so he can pretend he is doing a great job and give himself a pat on the back. Look! The streets are nice and clean. All the toxic glucose has been cleared. The fact that it has been crammed into all the houses escapes his attention.

This works for a short period of time, but eventually, the houses fill up again, and increases their resistance. Even the extra Insulin cronies cannot shove any more glucose in. What does Dr. Endo do? Get rid of some of the glucose instead of just moving it around? Stop glucose from coming into the city? Hardly. He has only learned one solution to every problem – give more insulin! To the man with a hammer, every problem looks like a nail. Year after year, the dosage of insulin relentlessly goes up.

The core problem of insulin resistance has been caused by excessive glucose and insulin. Yet the currently accepted solution is to prescribe even more insulin in order to lower blood glucose. Instead of eliminating the glucose, it merely moves it around the body into all the organs.

As these organs fill up with even more glucose, insulin resistance increases. However the higher dose of insulin only succeeds in creating more insulin resistance. The dosage of insulin is relentlessly increased to keep blood glucose levels down. Even while the symptom of high blood glucose improves, the disease of type 2 diabetes worsens. Taking higher and higher doses of insulin only means that the insulin resistance is getting worse and worse.

What happens over time? All our organs start rotting from excessive glucose. Insulin resistance develops precisely to shield against this toxic glucose load. The reason insulin resistance universally develops in all organs and in all peoples of the world is because it is protective mechanism. It’s a good thing, not a bad one. This is the answer to the question we posed in Chapter 3. Diabetes affects virtually every tissue in the body because we are cramming glucose into every nook and cranny.

A New Paradigm

The current paradigm of insulin resistance is a malfunctioning lock and key model. Glucose is stuck outside the cell and cannot get through the gate leading to ‘internal starvation’. Fifty years of devotion to this paradigm has utterly failed. In the interim, diabetes has risen to global epidemic proportions.

Understanding insulin resistance as an overflow phenomenon holds enormous treatment implications. Our current generation of medications, including insulin, sulphonylureas, and metformin do not address the underlying pathophysiology of type 2 diabetes. These medications, based on the old, failed paradigm are designed to ram glucose into the cells at all costs.

The primary problem is not insulin resistance. Instead, the root cause is hyperinsulinemia, forcing glucose into every tissue in the body. Giving more insulin to a patient with excessive insulin is harmful. We are inadvertently overcoming the tissue-protective insulin resistance that is developing.

Like giving alcohol to an alcoholic, prescribing insulin in a disease of excessive insulin is not a winning strategy. That’s exactly how we are losing the war on type 2 diabetes. This is how the ancient disease of type 2 diabetes has become the 21st century plague. It is because our fundamental understanding of the disease is flawed.

The problem is not insulin resistance. It’s the insulin, stupid!!

66 Responses

  1. Your analogies are wonderful, clear and humorous! Americans seem to better at understanding ‘alternate facts’ than most; your factual facts may not be grasped or accepted. 😉

    • What on earth are you talking about? Factual facts not “grasped” by Americans. Where do you think most of his audience is from? Get a grip.

      • I’d say @corrie has a firm grip and understands well Americans’ thirst for alternative facts, and failure to grasp factual facts. @Margot ironically and unwittingly proves the point. Hilarious.

  2. sten bjorsell

    Well done to find all those simple parables to explain what most of us including our doctors need to grasp.
    Many thanks and keep up the good work!

  3. Very entertaining and well conceived lesson on insulin resistance : )! Thank you : )!

  4. Well written explanation of type 2 diabetes and what to do about it.

  5. Sandra Rodriguez

    Now if only our doctors could read this.

  6. Sue and Tony

    Our doctor wouldn’t even give us a fasting insulin test. He said it was a waste of resources. Even though we said we would pay for it. He told us he wasn’t going to be told how to manage Tony’s health. WOW! Of course we no longer want his services.

    • sten bjorsell

      Well done! We all need to vote with our feet like you did!

    • I think that all of us need to remember that when we are leaving a practice for cause, that the practice and the doctor know why we are leaving.. Maybe if enough folk leave for the same reasons, the point will get across..

    • J L De Foa MD

      Your doctor probably doesn’t know how to interpret it – I have only learned in the past year. I figure if a $40 test can convince someone with high normal or “at risk” or “pre-diabetes” fasting glucose & HbA1c, or 2h 75 g glucose (in)tolerance test levels to reduce the fibre-free carbohydrate load in their diets and reverse the trend so I never have to prescribe a statin, or metformin, or schedule a stress test or an angiogram, or treat a foot ulcer, then it is $40 well spent to save perhaps thousands. I have about 50 results so far, from 16 (below the range!), or 21 (bottom of normal) to 352 pmol/L. The 21s were a 52 yo woman with fasting & 2h BS of 4.5, and a 55 yo woman with a fasting BS of 10.9. The first was fully insulin sensitive. The second needed perhaps triple the insulin production but her pancreas was already going into retirement and she was at the renal threshold for glucosuria – where Banting & Best would havesaid she had “diabetes Mellitus”, and she needs insulin, as well as a low carb diet, to get her metabolism controlled. The 352 was a tall 44 to make with a fasting BS of 7.8, who was thus using 18 times more insulin to do about half the job. What I have seen is a fasting insulin level in pmol/L less than one’s age is ok (21-40 is truly normal), while greater than age is often seen with glucose intolerance.

  7. So does fasting help you become more insulin sensitive? Or are your cells completely destroyed?

    • Sue and Tony

      A low Carb High Fat Diet (LCHF) plus fasting will completely reverse T2D. It has with my husband. Your beta cells aren’t destroyed they are just full of sugar and fat and can’t function. Dr. Fung addresses all of this in his blogs which I highly recommend you reading. They are life changing. dietdoctor.com explains how to eat LCHF completely.

  8. I am a new comer in the world of type 2 diabetes. I am sure there are a lot of two dollar words that these dr’s throw
    at us to explain our situation. Most of it goes in one ear and out the other. But Dr. Fung you are gifted in making it
    all understandable without using those words. I’m sure talking with your peers they will readily understand the
    medical terminology but to the patients out their your explanations,examples are spot on. My many thanks to you
    for your blog’s and you have enlightened me ten fold. I believe you have the ear of many many and still many people
    that will wish to express there thanks. Pls dont stop.

  9. Dennis Selby

    This excellent article has given me more of an understanding of how insulin resistance works than anything I’ve read in the past 10 years or so! Thank you so much for writing this!
    One other area that I have some trouble understanding is exactly HOW a Low Carb High Fat diet can help to reverse Type II Diabetes, ESPECIALLY when combined with intermittent fasting which I have been doing for some weeks now.
    It would really be helpful if you would write an article similar to this one explaining these two methods of “treating” insulin resistance.

    • Dennis, if you’re not eating many carbs (glucose), then your body won’t be sending insulin to remove it from your bloodstream. Fasting means your body has a prolonged period of not having to produce insulin.

      So, your body produces much less insulin when you eat low carb and none when you fast. Your insulin load will be a fraction of someone eating a standard diet, high in carbs and with no long gaps between meals. Hope that helps.

    • Dennis: Jason has written dozens of similar, excellent articles that will help understanding just that; continue to read the blog, and enjoy!

  10. Excellent! This is best explanation I’ve ever read of why the status-quo T2 treatments not only don’t work but make the disease much worse.

  11. A garbage truck is a PERFECT analogy, given that what many people eat is junk food!

  12. I love Fung’s work; however on one point I feel there is a need for a bit more. I have and read both his books carefully. The point is that its fructose which is 7 times more reactive than glucose that is the problem. It is metabolized only in the liver, thus 100% goes there, while only 20% of glucose goes there (See Prof, Robert Lustig’s Fat Chance). Following his lead, Insulin Resistance becomes a sign of a condition, just firemen are associated with a fire. The accumulation of fat in the liver, and for most they have NAFLD, None Alcoholic Fatty Liver Disease. The causal path is fructose damaging the liver, see Prof. Robert Lustig. See my website at http://healthfully.org/dja/id5.html

    • Dear Jerome,

      Dr fung has covered the fructose story in his many other blogs and gave scientific studies to prove the destructive powers of chemical fructose as oppose to natural fructose. In fact the issue goes a lot more than just fructose. It is chemicals that we find in almost all manufactured foods and our gmo foods that are filled with steroids and all kinds of chemicals .

      A simple solution is just to eat natural food. Anything god made cannot be bad, just how we use it and not go overboard

  13. Excellent Dr. Fung you’re the best many thanks for this greatly written analogy along with each one before. I’m so glad I have found this site can’t wait each week to see what you come up with next. Also, I’m glad to have found your blog before my diabetes got so bad it destroyed my organs, limbs, eyes etc. I have suffered with T2D for over 25 years I was quite young upon diagnoses and was part of the blame the victims by many different doctors.

    My wife can attest I have left doctors over bad advice many times but to this day I still can believe I had a doctor put me through “diabetes classes” for a second time because I didn’t get “it.” I was taught to make sure I eat between 45-60 grams of carbs at each meal 3 times a day along with a nightly snack that included 15-30 grams of carbs. Now that came out to 150-200 grams of carbs a day. No wonder I could not function as a human being.

    I don’t think now I eat 200 grams of carbs in a full month anymore thanks for telling it like it is.

  14. There is a Grassroots solution and that is .. SIMPLE.. DO NOT EAT CARBS.. if they do NOT go in, they can’t do damage.. ! You do manufacture the few you do need to function. Keytones can replace FUEL and food for your brain and body.
    People are Reversing Diabetes! Takes dedication, adjusting way of eating. Going clean on your intake of organic and simple foods. I am doing it and feeling great.. Diabetic type 2 medications only cover up the mess till later on down the pike..
    Read all you can and join some Grassroots forums so you can start learning HOW to take care of your body! No one else is going to do it! Talk to your doctor about changes to make.. My doctor understood.. Take charge! Best to you ALL!

  15. So… how come I don’t have much energy to spend, and feel always tired, even if my cells are full of glucose (and fat)?

    • When your insulin levels are raised, you can’t access the stored glucose and fat for fuel. This is one of the reasons intermittent fasting and extended fasts are recommended. Fasting lowers insulin levels which allows you to access stored fuel.

      • Yes, but the stored glucose is already accessed if it is inside the cell, right? Insulin is useful to get the glucose inside the cell, but now, according to this article, a lot of glucose is inside the cell, available to the mitochondria to burn, no need for insulin anymore, right? Still, the mitochondria doesn’t burn much of this glucose and doesn’t produce much energy, since I don’t have much energy to spare. So, what is gumming up my mitochondria and doesn’t let it burn the glucose and/or fat inside the cell? This is the million dollar question…

        • It’s more complicated than that. High insulin levels cause inflammation, and that may be the cause of fatigue. Also many people with insulin resistance report feeling exhausted after a carb-heavy meal. There’s so much more going on in the body than food in-energy out.

        • You can fast to turn your body over to fat burning and you will feel better. you can read Dr. Fungs complete guide to fasting and do a longer fast at first, it takes a couple days to burn off the glucose and turn on the fat burning.

    • sten bjorsell

      Think about an engine with a too rich fuel mixture. Hard to start, wont run well and if you get it going it soon blurs and stops. It also making lots of soot so that each run it goes poorer.

      • I think you are correct, and it is a good analogy, but how do I fix this? The fuel mixture is already too rich, as you say, and I’m already eating LCHF for a number of years. Still, energy is in short supply and fat is hardly budging. Yes, I know about fasting, unfortunately I’m the stray one that got sick from fasting (too much cortisol and now I’m broken)

    • Watch Lustig’s “Fat Chance” on youtube.

      Insulin blocks leptin signalling in the hypothalamus. Leptin is the hormone your fat cells release. It lets your brain know that you have ample energy reserves. This in turn results in your body reducing ghrelin (another hormone, that signals hunger and regulates energy usage). Simple terms: leptin lets your brain tell you to stop eating as well as feel free to burn as much energy as you need.

      When the brain isn’t receiving the signal from leptin, it proceeds as if you are starving. Which means it causes hunger (ghrelin) AND reduces non-essential energy usage (so as to conserve energy) until you get food. Insulin isn’t the direct problem, but it is a sort of master hormone that causes a cascade of other things to occur.

  16. Dr. Fung came on the scene just in time. Twelve percent of deaths in the USA attributed to diabetes – http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170219

    I hope he can get his message through to the sufferers of poor medical treatment in time to save them from MAAB (medicine as a business).

  17. …another MASTERPIECE! Thank you again!

  18. Can someone explain how obesity works in the Diabetesville model?

    • sten bjorsell

      In short, exactly like mainstream doctors treats it today. Early destruction and early death follows.

  19. Can someone explain to me what happens to the excess insulin in the blood AFTER the glucose were transferred into your cells? What is the “half life cycle” time of insulin, how does the body get rid of this excess insulin?
    PLEASE help with this question.

  20. So insulin resistance is a good thing, and doctors over come this by prescribing more insulin to ram more glucose into the already over full cells, so what do you suggest they do? While the patient continues to eat exactly what they want, because the whole nutrition advice given to them by the mainstream medical establishment continues to proscribe healthy eating as being a low fat high carb diet. How many of the 50% of pre-diabetic/diabetic people in America read this blog? How many doctors understand the perils of a high carb diet? How many people have to lose their eyesight, their limbs, their brain capacity before this is addressed? What is the average doctor to do when faced with a patient with a diabetic condition, follow the guidelines and prescribed insulin, if they don’t… what happens to the patient?

    • The patient dies a self induced death caused by complications from hyperinsulinemia. Blame at this point is moot. The irony is the person dies slower than if he takes the insulin “controlling” medications.

    • sten bjorsell

      Keith just said it. But more people are starting to question the unproven messages from main stream medicine, MSM. In Sweden there is a new Face Book group for diabetic people that quickly got over 6000 members. Some T1D members (that must take insulin) and also use automated blood sugar meters talk about reductions of insulin usage down to 1/5th of what it was, simply by seeing on the new meter how some foods drive up blood sugar more than others, then avoiding. I see there is one Face book group called “reversing diabetes” with over 20,000 members moving in same way. Then there are huge other established(?) FB groups. When links to this blog posted there and allowed to stay I think we will see the start of a healthy avalanche.

      • Sue and Tony

        Here in the States we have a Face Book page called Fung Shweigh inspired by Dr. Jason Fung. They are the best group of folks you could ever meet! Very supportive!

  21. Tim Heineman

    “insulin, sulphonylureas, and metformin do not address the underlying pathophysiology of type 2 diabetes.”

    I agree with the insulin and sulphonylureas part. But metformin’s mechanism is quite different upregulating, as it does, AMPK and therefore conversion of glucose to ATP. It doesn’t fit your metaphor.

    “do not address the underlying pathophysiology of type 2 diabetes” is a general statement that could apply to any pill, injection or surgery in that just about any intervention outside of lifestyle modification doesn’t address the etiology of the disease.

    • sten bjorsell

      Metformin may not worsen T2D. If we agree that key direct cause of high blood sugar in T2D is too much carbs, there is reduced need for metformin once carbs reduced. And although metformin is regarded safe it has lots of side effects which a low carb intake has not at all.
      (Note periodical fasting replaces metformin to get rid of high BS through emptying liver !)
      From Drugs.com: Side effects of metformin listed at Drugs. com
      More common:
      Abdominal or stomach discomfort
      cough or hoarseness
      decreased appetite
      diarrhea
      fast or shallow breathing
      fever or chills
      general feeling of discomfort
      lower back or side pain
      muscle pain or cramping
      painful or difficult urination
      sleepiness
      Less common:
      Anxiety
      blurred vision
      chest discomfort
      cold sweats
      coma
      confusion
      cool, pale skin
      depression
      difficult or labored breathing
      dizziness
      fast, irregular, pounding, or racing heartbeat or pulse
      feeling of warmth
      headache
      increased hunger
      increased sweating
      nausea
      nervousness
      nightmares
      redness of the face, neck, arms, and occasionally, upper chest
      seizures
      shakiness
      shortness of breath
      slurred speech
      tightness in the chest
      unusual tiredness or weakness
      wheezing

  22. You say it yourself, “Glucose and fructose are entering our body in excess of our energy needs”.

    Does the example of Diabetesville illustrate a diet high in carbohydrates, percentage wise, or a diet excess in carbohydrate, caloric wise?

    Even Dr. Lustig recommends whole grains.

    • sten bjorsell

      Fung already wrote “excess”in Diabetesville. Hence no question that Diabetesville is high in both carbs and calorie intake.

      Regarding the cause we know that a higher percentage modern (refined) carbs often results in highly variable blood sugars, which in turn sparks hunger between the standard 3 meals per day which easily can add up to 3 snacks per day and a night snack resulting in higher average insulin, which initself increases insulin resistance which then often leads to diabetes-2. Since the resulting higher average insulin makes it almost impossible to burn fat hunger results in more food which results in weight gain. Root cause to all: Simply too high percentage simple (fast burning) carbs in diet.

      Pigs have traditionally been fattened with low fat high carb feed: Skimmed milk and grains. It keeps them hungry and they eat all the time and fatten up quickly. There is no animal with a gastrointestinal system more similar to ours than pigs. Try lite milk and Kellog’s crunchy… The ads are actually true. The mixture is physically addictive as many from Diabetesville know too well.

  23. Is the ability to store fat protect us also against insulin resistance?
    I just read an article about Asians having a higher risk of developing diabetes despite staying thin.
    Is it possible that they have limited fat storage ability because their ancestors did have to survive the ice age as in Europe or desertic conditions as in Africa. For these populations, fat storage was essential for surviving the long periods of food shortage.
    I am just curious…..

  24. “because their ancestors did have to survive “….I mean ” because their ancestors did NOT have to survive “

  25. ELLEN PHAM

    <3 Add this to the "The 2 big Lies of Type 2 Diabetes" video and you've got a profound package to present to every newly diagnosed T2D.

  26. Roger Bird

    Excellent article. Jason illustrates what Einstein said: “Imagination is more important than knowledge. For knowledge is limited to all we now know and understand, while imagination embraces the entire world, and all there ever will be to know and understand.” Notice that Jason was not practicing the scientific method; he was not proving anything. He was using imagination to cover the known data points so much better and so much more reasonably than the conventional paradigm. And in the end, Occam always wins.

    However, I have to disagree with Jason somewhat. If there is too much sugar in the blood stream, everything else follows. And how does there get to be too much sugar in the blood stream? Because people are eating too much sugar and sugar producing substances (forget for a moment the role of stress and cortisol). It is really not rocket science, or even medical science. Too much sugar and sugar producing substances (carbs) puts too much sugar into the blood stream. Do this all of the time and the cells start to resist insulin and back ground levels of insulin build up, and then you are screwed.

  27. […] Insulin resistance protects against…insulin! T2D 26 […]

  28. Kristie Bowles

    My son is 16 and was diagnosed with insulin resistance at 7 along with metabolic syndrome. He was in the 25 percentile of height and weight until he fell off of a trampoline at the age of 5. He broke his elbow and wrist and had to have surgery that night. They put 3 pins in his elbow and one wrist. Then he tripple his weight in a year. He continued to gain weight. I asked doctors what happened and they told me it was where he was immobile when his arm was broken. Well nothing changed. We had to practicality tie him to the bed until he got a cast. He even moved the elbow inside the cast. We were afraid they were going to have to take him back to surgery. His school nurse notices the ring around his neck and called me and I told her I had tried to get then to do something and all they said was give him 2 % milk and watch what he eats. He has always ate well. He has been eating get salad since he had enough teeth to chew it. Tries every vegetable. Finally they sent us to an endocrinologist. She really didn’t do much but test his insulin and tell us it was 35 and should be 17. Told him how he should eat. Then she put him on METFORMIN. He has been seeing a pediatric gastrologist. He is still on the METFORMIN. Is that the same as giving him to much insulin and destroying his organs. If so he is coming get off of it. PLEASE HELP/REPLY. I just found out I am type 2 yesterday so things will be changing around my house.

    • Given your story, I would be concerned about metal allergy from the pins. No one triples their weight from being immobilized (anyways a cast does not immobilize a child). Or something else happened as well. Mold illness is another thing that can cause sudden massive weight gain. I admit these are “alternative” medicine ideas, but hey, conventional medicine may be wrong in more ways than one. Consider looking for a functional medicine physician (they are listed on the Institute for Functional Medicine “find a practitioner page”). I will leave this to your judgement. Read up and decide for yourself of course. I am biased since this is my work.

      • Kristie Bowles

        It is funny you say a metal allergy because I bought him a necklace for Christmas, which arrived late, and it is suppose to be sterling silver but I haven’t had it tested yet and he breaks out into a rash. Same with a ring he wanted to start wearing of his great grandfathers we had sized. He had to put it back on a piece of rope around his neck. He has alot of allergies but never thought it would cause him to gain weight with being in his bone. I was wondering about if he went into shock and if that trauma caused it. But NO one wanted to try to figure it out. Thank you for some insight to what it could have been.

        • Rosemary Gent

          may also like to look at a book”Dr Bernsteins Diabetes Solution” It has worked well for 8 years for me and has a lot of similarities to Diet Doctor. I am forever grateful that these sites exist

  29. To Kristie Bowles :Please go to dietdoctor.com and read as much as you can about how the LCHF diet works and watch also Dr Fung video.
    LCHF can reverse diabetes type 2 for you and your son.

    Good Luck!

  30. […] Insulin resistance protects against…insulin! T2D 26 […]

  31. Hi Dr Fung,

    Just wanted to share this with you, this is the by far the best diet advice I’ve ever heard from an MD. You’d do well to learn a thing or two from this:

    http://www.cbc.ca/radio/whitecoat/blog/don-t-ask-your-doctor-for-advice-on-nutrition-unless-1.3958279

  32. I remember that when I was a child (somewhere in the 80s and early 90s) folks here in Finland used to call diabetes something that literally translates into “sugar disease”. Diabetics were told to stay away from sugar. For example in parties we used to serve also sugar free food choices for them. Just wondering what happened that changed this. I cannot remember that were they also told to avoid other refined carbs, but just thought that this earlier recommendation to not eat sugar might be interesting.

  33. Hi Dr Fung and all LCHF believers out there ,

    Came across this study, you should check this out:

    https://www.ncbi.nlm.nih.gov/pubmed/28074888#cm28074888_52846

    This is what real science looks like. Not cherry picked data to support a theory that has been disproven for over 40 years just to sell and book written by a fraud.

  34. Great analogy Dr. Fung, although this only looks at one part of the ugly story that goes on here. Excess insulin not only leads to excess glucose in the blood but excess fat, and it is the poisoning that all of this excess fat causes that does us in the most, particularly what it does to our alpha cells, causing them to go haywire and excrete the massive levels of glucagon that is behind the high blood sugar of both type 2 and type 1 diabetes actually. Peripheral insulin resistance protects us from both. While we don’t want to be insulin resistant like this, the only real solution is to remove the threat, remove the need for such protection, treat the condition not just one of the symptoms! By the way I’m doing a series called Diabetes Basics on my site and I mentioned your analogy of treating an infection by just treating the fever, and we’re not stupid enough to do this with an infection, but we’re certainly stupid enough to use this approach in treating diabetes, and this would be funny if the results weren’t so sad. Keep up the great work and the great material!

  35. […] wanted to share with you a link to Dr. Fung’s latest blog post which is right down our alley, after I wrote the last segment of this one I decided to pay a visit […]

  36. B, you are right Kevin Hall is a fraud

  37. It absolutely HORRIFIES me that most doctors don’t know this and that they actually make people sicker. Makes me want to never go to a doctor again unless I’m deathly ill. If I’m not, I fear they’ll make me deathly ill. What is wrong with the medical profession and can’t somebody enlighten them???

    • This has its roots in the very philosophy of so called conventional medicine, allopathic medicine if you will. We seek to treat symptoms, not disorders. Diabetes is a perfect example, everyone wants to lower blood sugar, and they will ignore what is behind it, treating this symptom is enough. So we’ll pat ourselves on the back when we do this, and prescribe medications that do this in the short run, couple of years is great, wow this takes a point or two off your A1C, let me get my pad out, isn’t modern medicine wonderful.

      However this is all like treating the fever instead of the infection, the fever comes back, and it comes back worse. So when we look at the longer term results of these meds, they fail to even do what they are supposed to do, maintain blood sugar control, but if we just turn our heads and redouble our efforts we will erect enough of a facade to have us looking good in the eyes of our patients and the public.

      Of course there’s also the fact that corporate medicine has dominated the field and our physicians are trained to do their bidding pretty blindly, but some do wake up one day and see this for what it is, look at the actual science out there and also use some basic reasoning skills. The hardest person to see the light are the physicians themselves and it’s a real feat when we see some do, like Dr. Fung has.

      Ultimately, we are the ones that make the final decision about our own health care though, and it’s up to us to be wise as well, and one should not feel afraid about any of this, they should instead feel empowered to the extent that they understand that a more sensible and holistic approach should always be preferred.

  38. This lecture by Prof Babara Corkey provides some additional insights.
    https://www.youtube.com/watch?v=R453JTyBCK4

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